Oxytetracycline belongs to the group of tetracyclines and has bacteriostatic action against many Gram-positive and Gram-negative bacteria like Bordetella spp., Bacillus spp., Corynebacterium spp., Campylobacter spp., E. coli, Haemophilus spp., Pasteurella spp., Salmonella spp., Staphylococcus spp. and Streptococcus spp., and Mycoplasma spp., Rickettsia spp. and Chlamydia spp. The mode of action of oxytetracycline is based on inhibition of bacterial protein synthesis. Oxytetracycline is mainly excreted in urine and to a lesser degree in bile and in lactating animals in milk.